Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity
Figure 9
Bayesian networks of the impact of synthetic heterogeneity module phenotypes and rate constants on system performance value (S/N).
(A) Bayesian network inference using oscillator rate constants and phenotypes. (B) Bayesian network inference using throttle rate constants and phenotypes. Black arrows indicate the most direct connections between a node and S/N. The Bayesian inference describes phenotype groupings relevant to state values (blue), timing (yellow), and variability (red), along with the rate constants that control these phenotypes (green).