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Virtual Patients and Sensitivity Analysis of the Guyton Model of Blood Pressure Regulation: Towards Individualized Models of Whole-Body Physiology

Figure 10

The effects of aldosterone loading on the human body.

This simulation reproduced the conditions shown in Figure 5 of Uttamsingh et al. [74], which inclues experimental data from Davis and Howell [94] and Relman and Schwartz [76]. A: Extra-cellular fluid volume. B: Mean arterial pressure. C: Serum aldosterone (normalized). D: Sodium excretion rate.

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1002571.g010