Short Term Synaptic Depression Imposes a Frequency Dependent Filter on Synaptic Information Transfer

doi:10.1371/journal.pcbi.1002557

Short Term Synaptic Depression Imposes a Frequency Dependent Filter on Synaptic Information Transfer

Figure 6

Signal transfer at high and low frequencies.

The firing rate of a single presynaptic spike train () is modulated by the signal, , producing a postsynaptic conductance, . The coherence between the signal and conductance for (A) a slowly varying signal with peak frequency and (B) a quickly varying signal with . The stochastic model (solid blue) transmits the higher frequency signal more reliably than the lower frequency signal. The deterministic model (dashed red) transmits the signal with equal fidelity in both cases.

doi: https://doi.org/10.1371/journal.pcbi.1002557.g006