< Back to Article

Sarcomeric Pattern Formation by Actin Cluster Coalescence

Figure 1

Schematic depiction of sarcomeric organization in myofibrils.

Actin filaments (blue and red) are grafted at their plus-ends in an -actinin rich crosslinking band, termed the Z-band (green). The repetitive units spanning from one Z-band to the next are referred to as sarcomeres and measure in length. The myosin band (magenta) is traditionally called A-band, while the myosin-free part of the actin band is called I-band. Numerous auxiliary proteins ensure structural integrity and tune elastic properties.

doi: https://doi.org/10.1371/journal.pcbi.1002544.g001