Structural and Dynamic Requirements for Optimal Activity of the Essential Bacterial Enzyme Dihydrodipicolinate Synthase
Figure 5
A detailed view of the tight-dimer interface in E. coli and MRSA DHDPS.
Surfaces of both enzymes with the residues involved in the tight-dimer interface represented in light orange. Residues involved in hydrogen bonds are shown in red and in salt-bridges in yellow, as calculated by the PISA server (A) Dimer from E. coli wild-type tetramer (PDB ID: 1YXC); (B) MRSA wild-type dimer (PDB ID: 3DAQ).