Emergence of a Small-World Functional Network in Cultured Neurons
Figure 10
An increase in the number of links with high persistence as cultures aged.
Each histogram shows the percentage of links found at each link persistence level for all cultures at each age (normalized count of links found at the persistence value, expressed as the percentage of transient networks (bursts) in which the link was found, bin size 5%, bin edges specify the end of each bin). Top left: DIV 14, bottom left: DIV 21, top right: DIV 28, bottom right: DIV 35. Red (solid) line is the link persistence threshold (link presence in at least 25% of the transient networks). The histograms are cropped to show the detailed distribution, inset histograms show the full scale. At DIV 21, many links were found infrequently (i.e. below the link persistence threshold). The more pronounced tail of the distribution as the cultures matured, reflected a significantly higher contribution of persistent links in the network's of mature cultures.