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Emergence of a Small-World Functional Network in Cultured Neurons

Figure 6

The persistent network of a representative culture at DIV 14, 21, 28 and 35.

Graphs illustrate the spatial organization of network components at each culture age: the 8 by 8 grid corresponds to positions of the electrodes on the multi-electrode array (MEA). Nodes that are part of the network (i.e. for which a link was identified) are numbered according to their MEA hardware numbers, and the lines between electrodes represent un-directed links between nodes. Panel A: graphs from the networks thresholded at 25% link persistence. Panel B: graphs from the networks thresholded at 15% link persistence, this lower threshold results in more nodes and links.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1002522.g006