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A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath

Figure 10

The spatial distribution of anoikis and division events that occur in the epithelial layer when density-dependent inhibition of mitosis and random cell death are implemented.

(a) Anoikis events, (b) division events, (c) epithelial cell locations at the final timestep, (d) six typical migratory tracks for epithelial cells in the monolayer (showing the -coordinates only).

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1002515.g010