A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath
Figure 9
The spatial distribution of anoikis and division events that occur in the epithelial layer when density-dependent inhibition of mitosis is implemented.
(a) Anoikis events, (b) division events, (c) epithelial cell locations at the final timestep, (d) six typical migratory tracks for epithelial cells in the monolayer (showing the -coordinates only).