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Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases?

Figure 8

Distribution of radius of gyration of polyQ peptides.

(a) The estimated distribution for [red] and [blue]. (b) The estimated distribution for [red] and [blue]. The blue curve can be estimated as the sum [black] of three Gaussian distributions [dotted]. (c) The estimated distribution for , considering only the structures with an all-trans proline segment [green]. Similarly the green curve can be estimated as the sum [black] of four Gaussian distributions [dotted]. Considering only the structures that at least have one cis-proline results in the magenta curve for the distribution. All the histograms are obtained using a window of width . (d) The exponent in relation estimated from select pairs of (x axis) and ( for blue circles and for yellow squares). Inset: The average (in ) of Q peptides for .

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.1002501.g008