Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases?
Figure 6
Correlation analysis results for selected polyQ peptides.
Here is given the (a) odds ratio based between any two glutamine residues (
and
) of
[red] and
[blue] in terms of (
). From each side of the peptide
ending residues are omitted in the calculations to reduce the end effects. (b) Similar to (a) for
[red],
[blue], and
[black]. Here
residues from each end are omitted. (c,d) Correlation coefficient between
dihedral angles of any two glutamine residues (
and
) in terms of (
) for (c)
[red],
[blue] and (d)
[red],
[blue], and
[black]. The end residues were omitted according to the same protocol used for odds ratio analysis. (e,f) Similar to (a,b) but with the odds ratio calculated using the probabilities that residues belong or not to an
repeat region.