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Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases?

Figure 2

, PPII and content of selected polyQ peptides.

Here, given are the contents (as a percentage) of individual glutamine residues found in: (a,b) -region (c,d) PPII-region (e,f) . These percentages are plotted against the Glu residue numbers for (a,c,e) [red], [blue] and (b,d,f) [red], [blue]. These percentages are obtained from clustering the conformations based on their dihedral angles in the Ramachandran plot.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1002501.g002