Are Long-Range Structural Correlations Behind the Aggregration Phenomena of Polyglutamine Diseases?
Figure 1
(a) Schematic of amino acid backbone dihedrals
and
, and (b) a corresponding Ramachandran plot. In a typical Ramachandran plot of a glutamine residue, each pixel represents a
bin, whose intensity represents its relative population, ranging from 1,2,
,9, and 10 or more conformations, sampled in our simulations. Blue, yellow, grey, and pink clusters identify PPII,
,
, and
regions, respectively.