NIBBS-Search for Fast and Accurate Prediction of Phenotype-Biased Metabolic Systems
Figure 2
Schematic of key metabolic pathways for hydrogen production in Clostridium acetobutylicum.
Arrows with larger width indicate a series of reactions. Arrows with narrow width indicate individual reactions. Enzymes: 1, glycolytic enzymes; 2, pyruvate ferredoxin oxidoreductase (E.C. 1.2.7.1); 3, hydrogenase (E.C.1.12.7.2); 4, phosphotransacetylase (E.C. 2.3.1.8); 5, acetate kinase (E.C. 2.7.2.1); 6, acetyl-CoA acetyltransferase (thiolase) (E.C. 2.3.1.9); 7, -hydroxybutyryl-CoA dehydrogenase (E.C. 1.1.1.157); 8, crotonase (E.C. 4.2.1.55); 9, butyryl-CoA dehydrogenase (E.C. 1.3.99.2); 10, phosphotransbutyrylase (E.C.2.3.1.19); 11, butyrate kinase (E.C. 2.7.2.7). Abbreviations: Ferredoxin (Fd); Coenzyme A (CoASH).