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Impact of Adaptation Currents on Synchronization of Coupled Exponential Integrate-and-Fire Neurons

Figure 10

Effects of adaptation on spiking dynamics, - curves, PRCs and bifurcation currents of Traub model neurons.

A: Membrane potential of Traub model neurons without adaptation, (black), -mediated, (blue) and -mediated adaptation, (red), in response to step currents , B: the corresponding - curves, and C: the corresponding PRCs. Solid lines in C denote the PRCs, calculated with the adjoint method and scaled by 0.2 mV. Open circles denote the results of numerical simulations of eqs. (4)–(9) with 0.2 mV perturbations at various phases. D,E: Rheobase current (solid black), (dashed grey) and (dashed black), as a function of , for (left) and (right). and converge at marked by the red dot. The input current indicated by the green curve separates type I and type II PRC regions (blue and yellow, respectively). F,G: Spike frequencies according to the input currents in D and E. H,I: PRCs for parametrizations as indicated in F and G (with corresponding to ), scaled to the same period . All other model parameters are provided in the Methods section.

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1002478.g010