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Energetic Selection of Topology in Ferredoxins

Figure 3

Fold topology in a ferredoxin fold.

Right/Left fold configuration can be defined with an outlier, by orienting the outlier cysteine along the z-axis and iron-sulfur cluster being at the origin. A ferredoxin fold, with a conserved sequence CxxCxxC with an outlier cysteine, can create either right or left topological configuration. Right-handed fold is shown.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1002463.g003