Comprehensive Modelling of the Neurospora Circadian Clock and Its Temperature Compensation
Figure 5
Reproduction of wc-2ER24 mutant and wc-1−, qa-WC-1 behaviour.
(A) Simulated results showing levels of frq RNA and light-activated WCCn before and after a light to dark transfer. 10 data points/h are plotted. When the light (red line) is turned off after 50 h, frq mRNA levels oscillate. (B) Simulated frq mRNA behaviour of the wc-2ER24 mutant and (C) the wc-1−, qa-WC-1 strain. In (B) and (C) frq mRNA oscillates in the dark but the oscillation dampens with time.