Corresponding Functional Dynamics across the Hsp90 Chaperone Family: Insights from a Multiscale Analysis of MD Simulations
Figure 4
Distance fluctuation matrices for Grp94, Hsp90 and HtpG protomers in all different ligand states.
The magnitude of pairwise distance fluctuations is color coded from white (small fluctuations) to black (large fluctuations). The different absolute scale of pairwise fluctuations between Grp94, Hsp90 and HtpG reflects the different internal mobility of the three molecules.