Effect of Network Architecture on Synchronization and Entrainment Properties of the Circadian Oscillations in the Suprachiasmatic Nucleus
Figure 9
Effects of entrainment perturbations on the SCN composed of two regions.
(A) Effect of a 4-hour interruption of the light entrainment during the day (see arrow a ) on VL (blue) and DM (red) average
concentrations in the same SCN network as in figure 8. Dashed lines represent the unperturbed trajectories. (B) Effect of an 8-hour jet lag (long night, see arrow at
) on VL (blue), DM (red) average
concentrations (same network). Dashed lines represent the unperturbed trajectory shifted from 8 hours. (C–D) Average concentration of
at the extremum (points) of oscillations after an interruption of the light entrainment of 4 hours during the day (C), corresponding to panel A, or after a jet lag of 8 hours equivalent to a long night (D), corresponding to panel B. The average of VL cells is in blue and of DM cells in red. Dashed lines show unperturbed values. (E–F) Phase shift of the peak of
for the VL (blue) and DM (red) after an interruption of the light entrainment of 4 hours during the day (E), corresponding to panel A, or after a jet lag of 8 hours equivalent to a long night (F), corresponding to panel B. A positive value corresponds to a phase advance.