< Back to Article

Effect of Network Architecture on Synchronization and Entrainment Properties of the Circadian Oscillations in the Suprachiasmatic Nucleus

Figure 8

Simulation of the SCN composed of two regions in DD and LD conditions.

Simulation of the SCN with different architectures for the VL and DM regions (an coupled to an network, see Fig. S7 for a sketch of the topology), where the coupling constant between the DM cells is 0.15 and the DM cells are oscillating faster (see Models). (A–B) Phase difference of the cells in DD (A) and LD (B) conditions. Dots represent cells of the VL (beige region), whereas DM cells are small squares (light yellow region). Phase difference is color encoded: green corresponds to a phase delay, blue to a phase advance and red to antiphase (see also Fig. S13). (C–D) Concentration of in the individual VL (cyan lines) and DM cells (magenta lines), as well as the average over the VL cells (thick blue line), the DM cells (bold red line), and over the entire SCN (thick black line) in DD (C) and LD (D) conditions.

doi: https://doi.org/10.1371/journal.pcbi.1002419.g008