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Effect of Network Architecture on Synchronization and Entrainment Properties of the Circadian Oscillations in the Suprachiasmatic Nucleus

Figure 4

The different topologies tested.

Three types of networks are used in this work: random architecture (first row, ), scale-free architecture (second row, ) and local connections (last row, ). Note that the spatial distribution plays a role only in the ‘local’ networks. In the first column the corresponding adjacency matrix is shown (a black square at position represents a connection from the -th to the -th cell). In the second column, a representative network is drawn showing outgoing edges (blue lines) from certain cells (larger black circles) and a random distribution of light-sensitive cells (small yellow dots in the black circles). These networks are named , and respectively. In the third column, the network has a biased distribution of light-sensitive cells, either on the cells with a higher outgoing degree (for random and scale-free networks, first two row, named respectively and ), or spatially localized (for local networks, last row, named ).

doi: https://doi.org/10.1371/journal.pcbi.1002419.g004