Highly Sensitive and Specific Detection of Rare Variants in Mixed Viral Populations from Massively Parallel Sequence Data
Figure 2
Phase distance approached length of average read as coverage increased.
The phase distance was longer than half the average read length for loci covered more than 65-fold, and as coverage increased, it approached the length of the average read. The phase distance is a measure of how far apart phased variants can be and still be detected at lower frequencies than variants not in phase. We show the phase distance as a percentage of average read length.