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Impact of Network Structure and Cellular Response on Spike Time Correlations

Figure 3

The relation between correlation structure and response statistics in a feed-forward inhibitory microcircuit.

(A) The FFI circuit (left) can be decomposed into three submotifs. Equation (18) shows that each submotif provides a specific contribution to the cross-correlation between cells and . (B) Comparison of the theoretical prediction with the numerically computed cross-correlation between cells and . Results are shown for two different values of the inhibitory time constant, ( ms, solid line, ms, dashed line). (C) The contributions of the different submotifs in panel A are shown for both ms (solid) and ms (dashed). Inset shows the corresponding change in the inhibitory synaptic filter. The present color scheme is used in subsequent figures. Connection strengths were for excitatory and inhibitory connections. In each case, the long window correlation coefficient between the two cells was .

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1002408.g003