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Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies

Figure 4

Summary of Phylogenetic, Functional, Metabolite and Domain Architectures for Ntn-type Amide Hydrolase Superfamily.

The superfamily is divided into three structurally similar groups, with a diagrammatic version of the FunTree phylogenetic tree shown for each, as well as functional, substrate and multi-domain architecture data. Each domain is given a unique colour, with the domain of focus coloured green.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1002403.g004