Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans

doi:10.1371/journal.pcbi.1002379

Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans

Figure 10

Variation of period to the corresponding changes in stress and inhibition strength.

The inhibition strength K is varied from the lowest (0.8) to the highest value (1.7) in steps of 0.1 along the direction indicated by the arrow, and the bifurcation parameter is k. Inset shows the period of cortisol dynamics that varies between 23.5 and 24.5 for a very wide range of k values indicating the robustness of the system.

doi: https://doi.org/10.1371/journal.pcbi.1002379.g010