Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans
Figure 8
The correlation values between the dynamic sensitivities for the all the parameters are shown with the diagonal being self correlated. The levels of correlation are differently shaded as shown on the horizonal bar on the right that ranges from highly correlated (+1) to anti-correlated (−1). The sensitivities of the parameters of interest, namely k and K
are shown to be strongly and positively correlated, whereas the sensitivity of G
, the total glucocorticoid is strongly anti-correlated with respect K
, the strength of negative feedback loop in PTSD.