Multi-Scale Modeling of HIV Infection in vitro and APOBEC3G-Based Anti-Retroviral Therapy
Figure 7
Effects of HIV half-life and cell doubling time on virus infectivity rate and burst size.
(A) kinf decreases as tT,2 changes from 18 to 48 hours. The same trend is also observed as tv,1/2 increases from 4 hours to infinity. (B) Estimated burst size remains almost the same for different values of tv,1/2, however, it increases as tT,2 goes up.