Multi-Scale Modeling of HIV Infection in vitro and APOBEC3G-Based Anti-Retroviral Therapy
Figure 4
Degradation profile of protein entities in the model.
Using experimental data and first-order decay curves, degradation coefficients of (A) Vif, (B) A3G, and (C) A3G-Vif complex were estimated to be 0.25 hr−1, 0.1 hr−1, and 0.3 hr−1, respectively (re-plotted from Benedict et al. [60]).