Global Analysis of Small Molecule Binding to Related Protein Targets
Figure 4
Molecular weight and absolute differences in binding affinity.
Box plots show distributions of differences in binding affinity for small molecules grouped by equally sized molecular weight bins for paralogs. Each bin contains the same number of values and lower bin limits are shown below each box. Anova type multiple testing was carried out to assess the significance of differences between neighbouring groups and levels of significance are indicated with one (), two (
) or three asterisks (
).