Two Birds with One Stone? Possible Dual-Targeting H1N1 Inhibitors from Traditional Chinese Medicine
Figure 9
Protein-ligand interactions of TCM candidates and Tamiflu® in H1.
H1-ligand interactions following MD are illustrated for (A) Xylopine_2, (B) Rosmaricine_14, (C) Rosmaricine_15, and (D) Tamiflu®. Hydrogen bonds are indicated by green dashed lines between the atoms involved. Amino acids forming H-bonds with the ligand are shown in red. Hydrophobic contacts are represented by arcs with spokes radiating towards the ligand atoms they contact. The contacted atoms are shown with spokes radiating back.