Lipid Exchange Mechanism of the Cholesteryl Ester Transfer Protein Clarified by Atomistic and Coarse-grained Simulations
Figure 3
Electrostatic interactions between CETP and lipid droplet.
A) Number of salt bridges formed between the charged residues of CETP and the head groups of POPCs as a function of time. The upper profile shows the number of contacts between the positively charged residues and P atoms of POPCs, and the lower profile shows the number of contacts between the negatively charged amino acids and N atoms of POPCs. B) Salt bridge-forming positively (red) and negatively (blue) charged amino acids marked to the structure of CETP. Trp residues are labeled and green.