Role of Histone Tails in Structural Stability of the Nucleosome
Figure 11
Interaction of H2A C terminal extension (amino acids 100–129) with surrounding residues.
(A) Molsurfer [47] generated contact map of H2A C terminal docking domain (amino acids 100–119) interaction surface as derived from interatomic distances calculated from the structure averaged over the 100 ns of the intact nucleosome trajectory. Distances (in units of Å) are color coded as shown in the scale. Residues in close contact with H2A C terminus are indicated. (B) Positions of the H2A C terminal docking domain (colored red) close contact residues are shown in the nucleosome structure. The end of the H2A C terminus (amino acids 120–129) is colored magenta.