Role of Histone Tails in Structural Stability of the Nucleosome
Figure 10
Electrostatic potential maps of DNA and H3 N-terminal tail as seen by Arg81 and Arg88.
Potential is color coded (in units of Volts) as shown in the scale. (A) Snapshot from the intact nucleosome trajectory showing that in presence of the H3 N-terminal tail Arg81 and Arg88 points away from the DNA surface. The location of the -helix in H3 tail is shown in orange ribbons. (B) Snapshot from the H3 tail truncated simulation showing the Arg81 and Arg88 sidechain pointing towards the DNA in the absence of the H3 tail.