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Role of Histone Tails in Structural Stability of the Nucleosome

Figure 5

Structural changes in histone H2A(2) during tail-truncated simulations.

(A) Structure of histone H2A with position of the domain shown by thickened helix. (B) Upper panel. Order parameter for H2A(2) fold domain from three independent H3 tail-truncated nucleosome simulations. Lower panel. Order parameter for H2A(2) domain from the H3 tail-truncated nucleosome simulation 1. (C) Upper panel. Order parameter for H2A(2) fold domain from two independent H2A tail-truncated nucleosome simulations. Lower panel. Order parameter for H2A(2) domain from the H2A tail-truncated nucleosome simulation 1.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002279.g005