Role of Histone Tails in Structural Stability of the Nucleosome
Figure 2
Tail domains of the core histone proteins with positions where they were clipped indicated by lines.
In the tail-truncated nucleosome simulations the N-terminal tail domains of H3, H4, H2A and H2B were removed up to residues 26, 17, 11 and 20, respectively. For the H2A tail-truncated simulation the C-terminal residues 118–128 were also removed. Truncation sites for each tail were chosen at known trypsin cleavage sites [44].