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A Whole-Body Model for Glycogen Regulation Reveals a Critical Role for Substrate Cycling in Maintaining Blood Glucose Homeostasis

Figure 6

Time evolutions curves of selected enzymes and substrates.

A: Time response curves of GSa and GPa under two selected after glucose stimulus enters blood stream at in a glycogen depleted liver. Crossover of GSa and GPa occurs at 13.4 and 30.6 minutes respectively. B: Liver glycogen concentration plotted against time under the two selected .

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1002272.g006