A Whole-Body Model for Glycogen Regulation Reveals a Critical Role for Substrate Cycling in Maintaining Blood Glucose Homeostasis
Figure 3
Simulation results: dynamic responses of selected hormones and substrates during a 24-hour fasting period.
Note that hormone and substrate concentrations are normalized by their maximum values during the simulation. Blood glucose concentration has a multiplier of 0.8 to give a better view. Key: bl gluc = blood glucose; pl glucagon = plasma glucagon; pl ins = plasma insulin; pl FFA = plasma free fatty acids; bl ket = blood ketone bodies.