A Semi-Quantitative, Synteny-Based Method to Improve Functional Predictions for Hypothetical and Poorly Annotated Bacterial and Archaeal Genes
Figure 2
Synteny (gene order conservation) versus sequence divergence (average normalized bit score) in pairwise comparisons of 638 Bacterial and Archaeal genomes.
The phylogenetic pairwise comparison method was used to carry out 319 comparisons. See Text S1 for details.