Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing
Figure 4
A heat map of AIC scores for pre-mRNA, lariat-exon2 and mRNA.
A- indicates the AIC score for all species in Expt 1 (uncleaved and polyadenylated); U- AIC for uncleaved species in Expt 2; and P- AIC for polyadenylated species in Expt 2. The spectrum red to white reflects the lowest (best) to highest (worst) AIC score calculated for each species using the optimal parameter values for each pathway (rows I-VIII). Each column is normalised to have a minimum value of 0 by subtracting the minimum AIC score in the column from each entry.