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Computation of Steady-State Probability Distributions in Stochastic Models of Cellular Networks

Figure 1

A framework for combining intrinsic and extrinsic noise.

(A) Distribution prediction starts with predicting distributions based on intrinsic noise only and then adds in extrinsic noise. (B) A schematic for analysis of molecule number distributions in biochemical networks. Predicted distributions based on a model can be compared to experimental data, and information about parameters can be inferred.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1002209.g001