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Construction and Analysis of an Integrated Regulatory Network Derived from High-Throughput Sequencing Data

Figure 2

Topology of the integrated regulatory network in C. elegans.

The network contains 393 TFs (red circles), 160 miRNAs (cyan circles) and 5574 non-TF protein-coding genes (green circles). For 22 of these TFs, we determined the target genes and miRNAs. Topological features of the three node types were shown in the lower table.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1002190.g002