Long-Range Intra-Protein Communication Can Be Transmitted by Correlated Side-Chain Fluctuations Alone

doi:10.1371/journal.pcbi.1002168

Long-Range Intra-Protein Communication Can Be Transmitted by Correlated Side-Chain Fluctuations Alone

Figure 5

Correlation between residue 30 and other residues in calmodulin.

The extent of correlation between residue 30 (shown in black and circled) and all other side-chains in calmodulin (3cln [39]) is shown here. In (a) each residue is colored according to the magnitude of its excess mutual information with 30K (see left scale bar and Fig. 3). Coloring in (b) indicates the change in each residue's side chain entropy effected by the mutation K30G. Here, red represents increased entropy and blue decreased entropy (see right scale bar). See Methods for details.

doi: https://doi.org/10.1371/journal.pcbi.1002168.g005