A Mathematical Model of Muscle Containing Heterogeneous Half-Sarcomeres Exhibits Residual Force Enhancement
Figure 6
Heterogeneous passive tension properties also produce enhancement.
The standard stretch protocol was simulated with varying levels of passive (β) and active (α) variation among 50 half-sarcomeres connected in series. Each plot shows tension responses in stretch (red) and isometric conditions (blue). Inset numbers indicate the percentage of residual force enhancement after stretch for the given combination of β and α shown in the margins. Increasing just passive variation among half-sarcomeres (first column) gives rise to residual force enhancement behavior. When α and β are co-varied, it is apparent that the magnitude of enhancement is more sensitive to α.