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A Mathematical Model of Muscle Containing Heterogeneous Half-Sarcomeres Exhibits Residual Force Enhancement

Figure 5

Sensitivity of residual force enhancement to amount of half-sarcomere heterogeneity.

Residual force enhancement in a fiber composed of 50 half-sarcomeres in series as a function of α, the variation in half-sarcomere strength. Stretch magnitude was 8% of the final length. Note the logarithmic scale on the x-axis. As little as 2% variation in half-sarcomere strength produces 5% residual force enhancement following stretch.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1002156.g005