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A Mathematical Model of Muscle Containing Heterogeneous Half-Sarcomeres Exhibits Residual Force Enhancement

Figure 4

Force enhancement at different degrees of myofilament overlap.

(A) Residual force enhancement (RFE) as a function of final mean sarcomere length, simulated in a fiber containing 50 half-sarcomeres in series and an α value of 0.2. (B) Enhanced tension after stretch (circles) shown with the steady-state length tension curve produced by the model (solid line). Some enhancement can be seen on the ascending limb, plateau, and descending limb of the length tension curve.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1002156.g004