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A Peptide Filtering Relation Quantifies MHC Class I Peptide Optimization

Figure 2

Indexed reactions for a dynamical systems model of MHC class I peptide optimization.

Each shape in the model represents a molecular species and each box represents a reaction, where inbound edges represent reactants and outbound edges represent products. Boxes are labeled with corresponding reaction rates, where a single rate denotes an irreversible reaction and two rates denote a reversible reaction, with the rate of the forward reaction indicated on top. The subset of reactions taking place at the cell surface is given by (see Methods for the full reaction set).

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1002144.g002