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In Silico Evidence for Gluconeogenesis from Fatty Acids in Humans

Figure 3

Pathway for the conversion of fatty acids into glucose.

Essential reactions of the pathway are drawn with bold arrows. The presented pathway corresponds to the energetically most efficient pathway for the conversion of fatty acids into glucose (pathway 7 in Text S1). A similarly efficient pathway, pathway 14, uses almost the same route but converts acetol directly into methylglyoxal by reduction with NADPH. A list of abbreviations can be found in Table S1.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1002116.g003