Partially Glycosylated Dendrimers Block MD-2 and Prevent TLR4-MD-2-LPS Complex Mediated Cytokine Responses
Figure 9
Interaction of the partially glycosylated dendrimer's surface with human MD-2's surface.
Residues shown in red are <1.3 Å away from the surface of human MD-2. Glucosamine residues are shown in ball and stick configuration. (A) Side view of human MD-2's pocket; (B) frontal view of human MD-2's pocket.