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“Fluctuograms” Reveal the Intermittent Intra-Protein Communication in Subtilisin Carlsberg and Correlate Mechanical Coupling with Co-Evolution

Figure 6

The calculated hit rates ('s) and coverages ('s) by using Criterion-B, (eq.(3)).

(a) 's and 's from the apo fluctuogram. Hit rates achieved by randomly picking the same numbers as the selected residues are shown for comparison. (b) 's and 's from the Ca²⁺-bound fluctuogram.

doi: https://doi.org/10.1371/journal.pcbi.1002023.g006