Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations
Figure 5
Analysis of the binding mode of ImI to the α7-nAChR.
The structure of the binding pocket occupied by ImI after molecular dynamics simulation is displayed and positions discussed in the text are highlighted. The α7 principal subunit is in orange, the α7 complementary subunit is in pale yellow, and ImI is in violet. Nitrogens are in blue, oxygens are in red and sulfurs are in yellow.